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Oestrogen is produced mainly by the ovaries and is the dominant hormone in the first half of the
menstrual cycle. It is concerned with the development of the breasts and uterus at puberty. After this
its role is to build the uterine lining, or endometrium, each month prior to fertilisation as well as to
help regulate the menstrual cycle and normalise blood cholesterol levels

The stimulating effect of oestrogen helps to explain why it is toxic in excess.  Oestrogen stimulates
breast tissue; it can encourage the development of fibrocystic breasts.

If oestrogen is supplemented it increases the risk of breast cancer, it also stimulates the lining of the
womb, the endometrium, increasing the risk of endometrial cancer and the growth of fibroids.

The effects of Oestrogen:

  • Allows water and sodium into cells, thus affecting aldosterone production leading to water
  • retention and hypertension

  • Causes intracellular hypoxia (inadequate supply of oxygen to tissues)

  • Opposes the action of thyroid

  • Promotes histamine release

  • Promotes blood clotting

  • Increasing the risk of stroke or embolism

  • Thickens bile, promotes gallbladder disease

  • Causes copper retention and zinc  loss

  • If unopposed by progesterone, decreases libido

  • Increases the likelihood of breast fibrocysts, uterine fibroids, endometrial cancer and breast
  • cancer